Path of Exile · Setup guide

Path of Exile setup: choose PoE 1 or PoE 2

Start with your client: PoE 1 uses mouse movement, while PoE 2 lets you choose mouse movement or WASD. Set your controls first, then tune the loot filter and UI scale for readable fights.

Reviewed Oct 19, 2026 against community setups and manufacturer specs.

ScopePoE 1 & PoE 2
Last reviewed

MMOSetup / Layout notes

Start here: choose PoE 1 or PoE 2 before tuning controls

  1. Combat

    Can you reach movement and the actions your build actually uses?

  2. Loot

    Can you identify and select what you meant to pick up?

  3. Inventory

    Can you inspect, move, and organize items without fighting the controls?

  4. Trade / reference

    Can you reach the browser or reference you use, then return to the game?

A checklist, not a fixed sequence. Check PoE 1 and PoE 2 separately for input support and switching behavior.

Choose your version

PoE 1 and PoE 2 use different movement and menu assumptions.

Start with a loot filter and UI scale that make rare drops and defensive cues readable. Only then map movement, flasks, skills, and dodge on the input layer that matches the client you are running.

  • PoE 1: mouse movement with keyboard and side-button binds. See the keybind guide.
  • PoE 2: choose mouse movement or WASD first, then place skills. The same guide has a PoE 2 section.
  • Ultrawide, trade-screen, and handheld setup each have their own guide below.

By version

Pick the version on your account.

PoE 1 Mouse-led binds Filter and UI scale first, then map flasks and skills without crowding movement.
PoE 2 Mouse or WASD, then binds Lock movement mode in the keybind guide before comparing multi-button mice.
PoE 2 · optional Controller Combat can feel different from inventory and trade. Read the controller versus mouse/keyboard guide.
01 / Interface

Filter visual noise.

Update or swap the loot filter before buying display hardware. Use the official item-filter documentation for what the client supports today.

02 / Inputs

Keep defenses reachable.

PoE 1 and PoE 2 need separate checks for movement, flasks, skills, dodge, and menus. Add mouse buttons only when they fix a real bind conflict (see the keybind guide).

04 / Audio

Separate useful cues.

Keep boss and defensive cues audible over the rest of the map noise.

05 / Comfort

Support the long loop.

Long mapping and crafting sessions need a desk height and input layout you can hold for an hour without shifting every few minutes.

These mice are for keyboard-and-mouse play. If you don't need a full side grid, a standard mouse with a keyboard-led bind map is fine. Controller players should use the guide below instead.

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Peripheral options for Path of Exile 1 and Path of Exile 2
RoleProductFitTradeoffAmazon
Modular mouseRazer Naga V3 ProThree magnetic side plates with 12, 6, or 2 buttons; lockable ring-finger button.Setup uses Razer Synapse on Windows. Skip it if a fixed 12-button grid is enough.Razer Naga V3 Pro
Fixed 12-button mouseRazer Naga V2 HyperSpeedFixed thumb grid for mouse-led PoE 1 binds.The grid does not slide and can be more buttons than a PoE 2 WASD setup needs.Razer Naga V2 HyperSpeed
Open thumb-rest mouseLogitech G502 X LIGHTSPEEDOpen thumb ledge and programmable controls suit cursor aiming and keyboard binds.It does not have a 12-button thumb grid; pair it with keyboard binds and see Naga V2 HyperSpeed vs Logitech G502 X Plus.Logitech G502 X LIGHTSPEED
PC controller8BitDo Ultimate 2 BluetoothTMR sticks, switchable trigger modes, rear paddles, and extra bumpers.Stash management and trade whispers remain easier with a mouse and keyboard.8BitDo Ultimate 2 Bluetooth
Swappable side plates

Razer Naga V3 Pro

Choose it if switching between 12-, 6-, and 2-button side plates fits your PoE 1 and PoE 2 layouts. Skip it if a fixed grid is enough.

Check the Razer Naga V3 Pro
PoE / Controls

Controller or mouse and keyboard?

The PoE guide compares controller and mouse/keyboard tradeoffs across combat, inventory, trade, labels, and switching.

Read the guide

Guides for displays, controllers, and keybinds.

PoE / Keybinds

PoE keybind setup

Separate PoE 1 mouse binds from PoE 2 WASD, flask, skill, dodge, and controller decisions.

Read the guide

Guides for one specific job: ultrawide, Steam Deck, or a trade screen.

Compare

Head-to-head mouse, keypad, and controller comparisons

Use these when you are down to two specific models.

Equipment comparisons

Monitor comparisons

Compare multi-client space, refresh, and static-HUD tradeoffs.

FAQ

Path of Exile setup questions

Separate PoE 1 and PoE 2 before you copy binds or buy gear.

Should PoE 1 and PoE 2 use the same keybinds and mouse layout?

No. PoE 1 uses mouse-led movement with keyboard and side-button binds, making a 12-button grid useful. In PoE 2 you choose mouse movement or WASD first. With WASD, an open thumb-rest mouse like the Logitech G502 X or the 6-button or 2-button plate on the Razer Naga V3 Pro leaves thumb room while aiming.

What should I set first in a Path of Exile setup?

Pick the client on your account, then tune the loot filter and UI scale for readable fights. Run the combat, loot, inventory, and trade check before buying display hardware or a multi-button mouse.

Do I need an MMO mouse for Path of Exile?

Not by default. Add mouse buttons only when they remove a real bind conflict after movement, flasks, skills, and menus are mapped. A 12-button grid is most useful in PoE 1.

Can I play Path of Exile with a controller on PC?

Yes, both PoE 1 and PoE 2 support controllers on PC, including the 8BitDo Ultimate 2 Bluetooth or Razer Wolverine V3 Pro. Stash organization, crafting, and trade whispers remain faster with a mouse and keyboard.

Does PoE 2 use mouse movement or WASD?

You choose. Lock mouse movement or WASD in the client before mapping skills and defenses, and do not copy a PoE 1 mouse-only map onto a WASD layout.

What is the difference between the Razer Naga V3 Pro and Razer Naga V2 HyperSpeed?

The Razer Naga V3 Pro has three magnetic side plates with 12, 6, or 2 buttons, up to 23 programmable buttons including a lockable ring-finger button, a Focus Pro 50K Gen-3 sensor, and USB-C rechargeable power. The Razer Naga V2 HyperSpeed has a fixed 12-button grid with 19 programmable buttons and uses a replaceable AA battery.

Sources

Keep the PoE 1 and PoE 2 control paths separate.

PoE 1 uses mouse-led binds; PoE 2 players choose mouse or WASD. Check the game version before you copy a bind map or controller note from another guide.

SourcesPath of Exile homePath of Exile item-filter guidance

Compare mouse layouts

Use the mouse keybind visualizer after you choose the PoE client and input path.