How should I start mapping a 12-button MMO mouse?
Try the 12-button grid and place actions by comfortable reach. If Row 2 (Buttons 4, 5, and 6) is comfortable for your thumb, put three frequently used rotational skills there. Put AoE and short cooldowns on Row 1 (Buttons 1–3) and Row 3 (Buttons 7–9), then reserve Row 4 (Buttons 10–12) for longer cooldowns, potions, and mounts. If a row is hard to reach, adjust the map and test each bind.
