WoW
The twelve side buttons map to WoW Action Bar 1: keys 1 through 0, minus, and equals. One press should trigger one action under Blizzard's input-broadcasting policy, so map plain keypresses rather than multi-cast macros. Put your rotation on the row your thumb rests on, then stack Shift or Ctrl layers for cooldowns and defensives on other bars.
The grid layout is the same job on both mice; the decision is hand feel at about 170 g versus ~126 g on the cited listings, how you read each battery claim, and whether you will live in Redragon's Dual-Mode package or UtechSmart's Windows configurator. Follow the WoW MMO mouse setup guide to test reach before you bind every slot; the WoW setup hub covers the wider desk layout.
FFXIV
Map a twelve-slot hotbar one-to-one to the side grid. Players stack plain, Shift, and Ctrl hotbars; choose by which panel you can reach without changing grip.