The motion pattern is the whole story.
Where the movement happens
A mouse asks your arm and wrist to move the cursor across the
desk. A trackball asks your thumb to roll a ball while your
palm stays put. Neither is objectively better; they trade
different kinds of fatigue for different kinds of speed. Over a
short session the difference barely registers. Over
thousands of repeated clicks, the exact pattern of AFK OSRS
skilling, it adds up differently for each.
Precision at speed versus precision at rest
The G502 X's HERO 25K sensor and 13 programmable controls exist
to move a cursor fast and land it exactly where you want,
which is what tick-perfect combat and prayer-flicking demand.
The MX Ergo S tops out at 2048 DPI because it isn't built for
that kind of speed. It's built for controlled, repeated
pointing at the same few screen regions, which is closer to
clicking an inventory slot or a bank booth over and over.
One device, two different days
If your day is OSRS in the morning and spreadsheets in the
afternoon, the MX Ergo S carries the same low-arm-movement
benefit into both. The G502 X doesn't change behavior between
tasks. It's a fast mouse If you are combat training or
answering email, which is exactly why players who split time
between grinding and gaming often end up owning one of each.
For layout ideas on where either one sits relative to your
keyboard and screen, the OSRS setup hub
covers baseline desk positioning.